Applied Surrogate Endpoint Evaluation Methods with SAS and R Hardback
by Ariel (Maastricht University, Maastricht, Limburg, The Netherlands) Alonso, Theophile Bigirumurame, Tomasz (Hasselt University, Belgium) Burzykowski, Marc Buyse, Geert (Universiteit Hasselt & KU Leuven, Belgium) Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv (Hasselt University, Belgium) Shkedy, Wim Van der Elst
Part of the Chapman & Hall/CRC Biostatistics Series series
An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment's efficacy.
When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way.
This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.
- Format: Hardback
- Pages: 374 pages
- Publisher: Apple Academic Press Inc.
- Publication Date: 13/12/2016
- Category: Clinical trials
- ISBN: 9781482249361