Troubleshooting LC Systems : A Comprehensive Approach to Troubleshooting LC Equipment and Separations Hardback

Over the last 15 years, high-performance liquid chromatogra­ phy (LC) has made the transition from an instrument used only by experts in research labs to a tool used for routine applications by relatively unskilled workers.

With this transition have come in instrumentation and column technology.

In major advances the past, the operator had to be a jack-of-all-trades, with a screw­ driver, soldering iron, and various wrenches as constant compan­ ions in the LC lab.

Today, many instruments contain micropro­ cessors as powerful as those of mainframe computers of earlier days.

With this technology has come a variety of self-diagnostic tools that allow the LC system to locate many of its own prob­ lems.

Traditionally, well-honed LC troubleshooting skills have been a result of years of work at the bench.

Today the LC system itself often can do a better job of troubleshooting than the operator can.

Yet many of the problems of the past are still the major problems of today: air bubbles, check valves, detector lamps, and, of course, problems with the separation.

An added pressure on the operator of today's LC system is that of productivity-the lab often cannot afford unnecessary downtime.

This means that the operator has to be a troubleshooting expert, or has to have that expertise at his or her fingertips.

The present book was written to provide this expertise in an easy-to-use format for users at all levels of experience.