Randomization in Clinical Trials : Theory and Practice Other digital
by William F. Rosenberger, John M. Lachin
Other digital
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Description
This book offers a unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications.
The role of randomization techniques in clinical trials has become increasingly important.
This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization.
Taking an unabashedly non-Bayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihood-based inference as it relates to sufficiency and ancillarity.
Developments in stochastic processes and applied probability are also given where appropriate.
Intuition is stressed over mathematics, but not without a clear development of the latter in the context of the former.
Providing a consolidated review of the field, the book includes relevant and practical discussions of: the benefits of randomization in terms of reduction of bias; randomization as a basis for inference; covariate-adaptive and response-adaptive randomization; and, current philosophies, controversies, and new developments. With ample problem sets, theoretical exercises, and short computer simulations using SAS, "Randomization in Clinical Trials: Theory and Practice" is equally useful as a standard textbook in biostatistics graduate programs as well as a reliable reference for biostatisticians in practice.
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Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Other digital
- Publisher:John Wiley and Sons Ltd
- Publication Date:28/01/2005
- Category:
- ISBN:9780471722106
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Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Other digital
- Publisher:John Wiley and Sons Ltd
- Publication Date:28/01/2005
- Category:
- ISBN:9780471722106