Advances in Perinatal Medicine : Volume 5 PDF
Edited by E. Friedman, L. Gluck, Aubrey Milunsky
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The state of health care is reflected by perinatal and neonatal morbidity and mortality as well as by the frequencies of long-term neurologic and developmental disorders.
Many factors, some without immediately rec- ognizable significance to childbearing and many still unknown, undoubt- edly contribute beneficially or adversely to the outcome of pregnancy.
Knowledge concerning the impact of such factors on the fetus and sur- viving infant is critical.
Confounding analyses of pregnancy outcome, especially these past two or three decades, are the effects of newly un- dertaken invasive or inactive therapeutic approaches coupled with the advent of high technology.
Many innovations have been introduced with- out serious efforts to evaluate their impact prospectively and objectively.
The consequences of therapeutic misadventures characterized the past; it seems they have been replaced to a degree by some of the complications of applied technology.
Examples abound: after overuse of oxygen was recognized to cause retrolental fibroplasia, its restriction led to an in- crease in both neonatal death rates and neurologic damage in surviving infants.
Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dos- age, occasionally resulted in kernicterus.
Prophylactic sulfonamide use had a similar end result.
More recent is the observation of bronchopul- monary dysplasia as a complication of respirator therapy for hyaline membrane disease.
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- Format:PDF
- Publisher:Springer US
- Publication Date:11/11/2013
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- ISBN:9781461594680
Information
-
Download Now
- Format:PDF
- Publisher:Springer US
- Publication Date:11/11/2013
- Category:
- ISBN:9781461594680