Extracellular Matrix and The Liver : Approach to Gene Therapy, PDF eBook

Extracellular Matrix and The Liver : Approach to Gene Therapy PDF

Edited by Isao Okazaki, Yosifumi Ninomiya, Tanikawa Kyuichi, Scott I. Friedman

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Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discussesnew strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapyapproaches.

The chapters are divided into six sections as follows:

  • Basic Science of Extracellular Matrix
  • Cells Responsible for Extracellular Matrix Production
  • Activation Mechanism of Hepatic Cells and Signal Transduction
  • Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors
  • Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases
  • New Strategies for the treatment of Liver Cirrhosis
  • Discusses the possibility of gene therapy for liver cirrhosis
  • Includes information on new aspects of hepatic stellate cells
  • Written by top experts in basic science and clinical hepatology

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