RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways : Volume 449 Hardback
Edited by Lynne E. (University of Rochester, NY, USA) Maquat, Megerditch (Rutgers University, New Brunswick, NJ, USA) Kiledjian
Part of the Methods in Enzymology series
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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences.
Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression.
Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.